Hyalase® (hyaluronidase 1500 units) is a prescription only formulation, licensed and commonly used to boost absorption or dispersal of drugs injected into the skin and has an off license use in aesthetic medicine.
Hyaluronic Acid (HA) fillers are sterile gels consisting of non-animal stabilised hyaluronic acid for injection into the skin to correct facial lines, wrinkles and folds, for lip enhancement and for shaping facial contours. Hyaluronidaise is an enzyme which breaks down hyaluronic acid. Hyaluronic acid is the component of dermal fillers, but is also naturally occurring in the skin and soft tissues.
Occasionally dermal fillers need to be dissolved when the treatment outcome is unacceptable, when an adverse reaction to the implant has occurred, or there is a possibility of vascular occlusion and/or impending necrosis (tissue death) which could lead to the compromise of healthy tissue.
Not everyone is suitable for this treatment. The practitioner will take a detailed medical history to ensure you have no conditions that might increase risk of unwanted side effects, consultation is also important to discuss your expectations and whether or not this treatment is able to meet them. A history of certain allergies may present an unacceptably high risk of serious allergic reaction to Hyalase®. If you are unhappy with dermal filler treatment you have received elsewhere, it may not be appropriate for another practitioner to use Hyalase®, without a referral letter. It is important the risks do not outweigh the benefits and a good outcome is achievable.
The treatment is administered by injection, but topical anaesthetic can be used to numb the skin. Your practitioner will discuss options for your comfort at consultation.
All make up will need to be removed prior to treatment, so please come ‘fresh faced’ if possible. Alcohol, aspirin, Ibuprofen and a range of dietary supplements including; St. Johns Wort, fish oils, Gingko Biloba, Vitamins C and E- may all contribute to bruising and are best avoided 24 hours before treatment. Treatment cannot be administered if there is an active skin infection, including acne or cold sores or if you are unwell- including colds, coughs, sore throats etc. Do contact the clinic to discuss any illness or new medicines prior to attending.
If you are receiving Hyalase® treatment to correct unsatisfactory results, you will be given a test dose (a small injection on your forearm) and observed for a minimum of 20 minutes, to identify any sensitivity which may indicate allergy to Hyalase®. If symptoms of sensitivity are observed then treatment cannot proceed.
Any over correction resulting from the loss of your own hyaluronic acid will usually be temporary and is expected to recover within a few days. The breakdown of the dermal filler will be permanent.